Limiting dietary iron intake can slow tumour growth and increase the efficacy of some cancer therapies, according to a new animal study. Researchers used mouse models to demonstrate that iron depletion can weaken tumours by increasing their dependency on angiogenesis, making them less able to resist antiangiogenic therapies. Iron reduction may therefore provide a simple and effective way of enhancing current therapies in patients with cancer. However, the lack of data regarding the survival of the mice means it is difficult to apply these findings to humans.
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