Expert Comment

Maternal iron deficiency, anaemia and common mental disorders (CMD) have adverse consequences on subsequent infant motor development, a new study in Vietnam indicates. The findings highlight the need to improve the quality of antenatal care for pregnant women in low- and middle-income countries.

Patients scheduled for major elective orthopaedic procedures frequently present with preoperative iron deficiency and anaemia1,2. Iron deficiency anaemia is the most common form of anaemia and preoperative anaemia has been linked to higher postoperative infection rate, poorer physical functioning and recovery, decreased quality of life, and increased length of hospital stay (LOS) and mortality1–5.

Intravenous iron may improve erythroid recovery in patients treated with DA after haematopoietic cell transplantation (HCT). Darbepoetin alfa (DA) helps to ensure full erythroid reconstitution after autologous HCT when started on day 28 post-transplant, a new study indicates.

Laparoscopic Roux-en-Y gastric bypass (LRYGB) is the most widely used procedure for the surgical treatment of obesity in the USA.  Reduced iron absorption is an expected consequence of this surgical intervention due to exclusion of the duodenum and proximal jejunum resulting in reduced iron absorption, diminished exposure of food to gastric acidity and reduced dietary intake1.

Both iron deficiency and iron overload correlate with organ impairment in patients with multiple myeloma, but iron deficiency is observed more frequently according to recent findings, study authors report.

Approximately 97% of patients with multiple myeloma develop anaemia during the course of their disease. Usually, anaemia in these patients is normocytic/normochromic, combined with normal to low iron levels and elevated ferritin levels.

20Jeong et al recently reported the results of a retrospective observational study of 527 patients undergoing gastrectomy for gastric carcinoma. Patients with acute postoperative anaemia (haemoglobin <10 g/dL) received intravenous iron sucrose. Patients with preexisting, preoperative anaemia were excluded. A dose of 300 mg was administered every other day until reaching the total target amount, calculated as:

(body weight x [target haemoglobin – current haemoglobin] x 0.24) + 500 mg


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