Iron deficiency

A new study demonstrates that there is a high prevalence of anaemia in patients with advanced chronic kidney disease, which increases in the later stages of the disease. The authors suggest that control of anaemia may be achieved with moderate doses of erythropoietin stimulating agent (ESA) and iron therapy, as per current guidelines.

Maternal iron deficiency, anaemia and common mental disorders (CMD) have adverse consequences on subsequent infant motor development, a new study in Vietnam indicates. The findings highlight the need to improve the quality of antenatal care for pregnant women in low- and middle-income countries.

Patients scheduled for major elective orthopaedic procedures frequently present with preoperative iron deficiency and anaemia1,2. Iron deficiency anaemia is the most common form of anaemia and preoperative anaemia has been linked to higher postoperative infection rate, poorer physical functioning and recovery, decreased quality of life, and increased length of hospital stay (LOS) and mortality1–5.

Recent research has ascertained that, although iron deficiency is common in patients with chronic obstructive pulmonary disease (COPD), it is not routinely tested for or treated. It has also been shown that treating these patients with erythropoietin stimulating agents (ESAs) or intravenous iron not only corrects the iron deficiency but also improves symptoms of dyspnoea.

Laparoscopic Roux-en-Y gastric bypass (LRYGB) is the most widely used procedure for the surgical treatment of obesity in the USA.  Reduced iron absorption is an expected consequence of this surgical intervention due to exclusion of the duodenum and proximal jejunum resulting in reduced iron absorption, diminished exposure of food to gastric acidity and reduced dietary intake1.

A new study indicates that oral iron therapy results in failure to control iron deficiency anaemia in two out of three patients with inflammatory bowel disease. Researchers suggest alternative options should be considered in these patients and, in particular, administration of intravenous iron therapy.

Patients with colon cancer are more likely to experience comorbidities if they also present with iron deficiency anaemia, a new study indicates. Researchers suggest that inferior survival outcomes could be due to a higher prevalence of diabetes, cardiovascular disease, and chronic kidney disease.

Short-term food restrictions in women can cause iron deficiency and alter emotional status, according to researchers. Authors of the new study suggest that depressive symptoms in disorders where food is restricted, such as anorexia or other eating disorders, may be associated with iron deficiency.

Both iron deficiency and iron overload correlate with organ impairment in patients with multiple myeloma, but iron deficiency is observed more frequently according to recent findings, study authors report.

Approximately 97% of patients with multiple myeloma develop anaemia during the course of their disease. Usually, anaemia in these patients is normocytic/normochromic, combined with normal to low iron levels and elevated ferritin levels.


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