Maternal iron deficiency during pregnancy can lead to iron deficiency in infants, with potentially lifelong consequences, a new article indicates. The review explored iron status throughout the ‘first 1000 days’ from pregnancy through to two years of age, and emphasised the importance of identifying and treating iron deficiency, in addition to underlining remaining research gaps.

Iron therapy may be recommended during pregnancy for patients who have undergone liver or kidney transplant, new research indicates. The authors of the literature review recommend a haemoglobin level of 10–12 g/dL as a therapeutic goal in this patient group, to be achieved using erythropoietin-stimulating agents (ESAs) and iron therapy. They explain that management of anaemia may help to prevent preterm delivery.

New data reveals an increased risk of iron deficiency and iron deficiency anaemia in premenopausal women who are of Asian ethnicity, regularly donate blood and who have a previous history of iron deficiency. The analysis also indicates that dietary patterns have a smaller, but still substantial, effect on the risk of developing the condition.

Single-infusion ferric carboxymaltose improves symptoms of fatigue in iron deficient women with normal or borderline haemoglobin, new data reveal. The PREFER trial (Ferric Carboxymaltose Treatment to Improve Fatigue Symptoms in Iron-deficient Non-anaemic Women of Child Bearing Age) also demonstrates that ferric carboxymaltose may improve mental quality of life (QoL), cognitive function and erythropoiesis compared with placebo. Researchers suggest that ferric carboxymaltose may be an effective treatment alternative in patients who cannot tolerate or use oral iron.

New study data indicate that intravenous iron may improve health-related quality of life in women who have iron deficiency anaemia caused by abnormal uterine bleeding. In addition, treatment with ferumoxytol, where oral iron has previously been unsuccessful, increases haemoglobin levels in this patient group, according to the researchers.

A significant association has been found between iron status and psychological distress in young Japanese women, according to a new article. The results highlight an increased risk of anger, fatigue and tension in women with iron deficiency without anaemia (IDNA). The authors suggest that IDNA may be a risk factor for mental health problems in this patient group.

Iron deficiency without anaemia (IDNA) frequently affects women of reproductive age. This study aimed to determine the relationship between IDNA and mental health and somatic symptoms.

Iron deficiency is associated with a range of symptoms that are not only detrimental to women’s quality of life, but may also have a negative impact on clinical outcomes, including the health and wellbeing of offspring in the case of pregnant women1. When severe, iron deficiency can result in iron deficiency anaemia, which has a negative effect on patient vitality that is comparable with chronic diseases including clinical depression and chronic kidney disease (see figure below).

Maternal iron deficiency, anaemia and common mental disorders (CMD) have adverse consequences on subsequent infant motor development, a new study in Vietnam indicates. The findings highlight the need to improve the quality of antenatal care for pregnant women in low- and middle-income countries.


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